Shopping Search

Salient Features: A companion to Textbook of Medical Biochemistry by the same author, Simple, short and accurate answers to the questions generally asked in viva voce, Useful for confidence building, Covers the questions not only related to theory but also the table-viva related to practical problems, A new chapter on Acid Base Balance and Imbalance has been added. Dr (Brig) MN Chatterjea Is an eminent author. His book Textbook of Medical Biochemistry is very popular not only in SAARC countries but also in the Gulf. Another titles Clinical Chemistry: Organ Function Tests, Laboratory Investigations and Inborn Metabolic Diseases has just been released. 1. Chemistry of Carbohydrates, 2. Chemistry of Lipids and Eicosanoids, 3. Chemistry of Proteins and Amino Acids, 4. ImmunoglobulinsChemistry and Functions, 5. Chemistry of Nucleotides and Nucleic Acid, 6. Chemistry of Enzymes, 7. Biologic Oxidation, 8. Chemistry of Hemoglobin and Hemoglobinopathies, 9. Vitamins, 10. HemeSynthesis and Catabolism, 11. Digestion and Absorption, 12. Metabolism of Carbohydrates, 13. Metabolism of Lipids, 14. Metabolism of Proteins and Amino Acids, 15. Metabolism of Nucleoproteins, 16. Detoxication, 17. Metabolism of Minerals, 18. Hormones: Chemistry and Functions, 19. Protein Synthesis, DNA Replication and DNA Recombinant Technology, 20. Chemistry of Respiration, 21. Biophysics, 22. Radioactivity: Radio-isotopes in Medicine, 23. Clinical Enzymology, 24. Biochemistry of Cancern, 25. Acid Base Balance and Imbalance.

For more than two decades, this work has remained the leading advanced textbook and easy-to-use reference on food chemistry and technology. Its fourth edition has been extensively re-written and enlarged, now also covering topics such as BSE detection or acrylamide. Food allergies, alcoholic drinks, or phystosterols are now treated more extensively. Proven features of the prior editions are maintained: Contains more than 600 tables, almost 500 figures, and about 1100 structural formulae of food components - Logically organized according to food constituents and commodities - Comprehensive subject index. These features provide students and researchers in food science, food technology, agricultural chemistry and nutrition with in-depth insight into food chemistry and technology. They also make the book a valuable on-the-job reference for chemists, food chemists, food technologists, engineers, biochemists, nutritionists, and analytical chemists in food and agricultural research, food industry, nutrition, food control, and service laboratories. From reviews of the first edition "Few books on food chemistry treat the subject as exhaustively…researchers will find it to be a useful source of information. It is easy to read and the material is systematically presented." JACS

A textbook for graduate or advanced undergraduate students, and a reference for researchers whose training in not is glycobiology but who are moving into the field. Emphasizes the biosynthetic pathways that result in a wide variety of identified protein-bound oligosaccharides. First overviews the chemical structures of monosaccharides and oligosaccharides to provide a scientific basis for the subsequent material. Then discusses the purification, function, and enzyme kinetics of selected glycosidases and glycotransferases; the role of oligosaccharides in glycoprotein function; the in-vivo role of glycoproteins themselves; the in-vitro synthesis of glycoproteins; and future directions in glycobiology. Annotation c. by Book News, Inc., Portland, Or.

US and European biological and medical researchers offer a reference and textbook on the connexin family of membrane channel proteins. The first section looks at the biology of the proteins, including genetics, structure, biophysics, electro-physiology, and cell biology. Specific topics there include gap junction channel structure, the chemical gating of connexin channels, electrical signaling with neuronal gap junctions, and pharmacology. A second section explores roles of connexin channels in various organ systems or processes, among them skin biology, the respiratory epithelium, the inner ear, female and male reproduction systems, secretion, and carcinogenesis. The length of the volume prevented more than passing reference to the role of connexins in the immune system and in hematopoiesis, and the possible non-channel functions of the protein. No mention is made of the accompanying disk, except that it is copyrighted. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)

This new edition of Essentials of Clinical Psychopharmacology is a synopsis and update of the most clinically relevant material from The American Psychiatric Publishing Textbook of Psychopharmacology, Third Edition. The Essentials focuses on the aspects of psychopharmacology directly related to clinical care and will appeal to psychiatry residents, primary care physicians, and others interested in a concise tutorial on clinical psychopharmacology. The book is organized around two major sections of the Textbook. The first section, Classes of Psychiatric Treatments, presents information by classes of drugs and greatly expands on the first edition of the textbook by focusing whole chapters on single drugs in the antidepressant, antipsychotic, and bipolar categories. For each drug within a class, data are reviewed on preclinical and clinical pharmacology, pharmacokinetics, indications, dosages, side effects and toxicology, and drug-drug interactions. Included are data on currently available drugs in the United States and medications that will almost certainly become available in the near future. The second section, Psychopharmacological Treatment, provides specific information about drug selection and prescription and reviews state-of-the-art therapeutic approaches to the treatment of patients with major psychiatric disorders. Also reviewed are pharmacotherapeutic approaches for special populations, such as children and adolescents, medically ill patients, and the elderly. Chapters are devoted to pharmacotherapy in special situations, such as during pregnancy and lactation and in psychiatric emergencies. This section provides the reader with specific information about drug selection and prescribing practices. In addition to the clinical focus of the Essentials, the authors have provided new information based on more recent literature available since publication of the Textbook. Included are updates on the effectiveness and availability of specific drugs and therapeutic approaches.

This introductory textbook of pharmacoeconomics is ideal for all those working in, aspiring to work in or interested in the pharmaceutical industry. It assumes no prior knowledge of this subject but is written at a level appropriate, for example, for those studying for a postgraduate degree or diploma in pharmaceutical medicine and who already have a first degree in science or medicine.Emphasizes how pharmacoeconomics can be of assistance in "real world" decision making.Covers the development of insuring, financing and delivery of health care in the developed world and the increasing role of governments.Explains the trend towards the critical scrutiny of health service activity.All topics explained assuming no specialist knowledge.

This unique and much needed textbook meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker, et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, Pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. *Uses individual drugs to explain molecular actions*Full color art program explains molecular and chemical concepts graphically*Logical structure reflecting the current state of pharmacology and translational research, starting with receptors and finishing with target molecules*Covers such intricacies as drug resistance and cell death*Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

Volume 1: Reducing and managing humanity's demand for energy is a fundamental part of the effort to mitigate climate change. In this, the most comprehensive textbook ever written on the subject, L.D. Danny Harvey lays out the theory and practice of how things must change if we are to meet our energy needs sustainably. The book begins with a succinct summary of the scientific basis for concern over global warming, then outlines energy basics and current patterns and trends in energy use. This is followed by a discussion of current and advanced technologies for the generation of electricity from fossil fuels. The book then considers in detail how energy is used, and how this use can be dramatically reduced, in the following end-use sectors: - buildings - transportation - industry - food and agriculture - municipal services The findings from these sector-by-sector assessments are then applied to generate scenarios of how global energy demand could evolve over the coming decades with full implementation of the identified and economically-feasible energy-saving potential. The books ends with a brief discussion of policies that can be used to reduce energy demand, but also addresses the limits of technologically-based improvements in efficiency in moderating demand and of the need to re-think some of our underlying assumptions concerning what we really need. Along with its companion volume on C-free energy supply, and accompanied by extensive supplementary online material, this is an essential resource for students and practitioners in engineering, architecture, environment and energy related fields. Online material includes: Excel-based computational exercises, teaching slides for each chapter, links to free software tools. Volume 2: Transforming our energy supplies to be more sustainable is seen by many to be the biggest challenge of our times. In this comprehensive textbook, L.D. Danny Harvey sets out in unprecedented detail the path we must take to minimize the effects that the way we harness energy will have on future climate change. The book opens by highlighting the importance of moving to low carbon technologies for generation, then moves on to explain the functioning, potential and social/environmental issues around: - solar energy - wind energy - biomass energy - geothermal energy - hydroelectric power - ocean energy - nuclear energy It also covers the options for carbon capture and storage and the contexts in which low carbon energy can best be utilized (potential for community integrated systems, and the hydrogen economy). The book closes with scenarios that combine the findings from its companion volume (concerning the potential for limiting future energy demand) with the findings from this volume (concerning the cost and potential of C-free energy systems) to generate scenarios that succeed in limiting future atmospheric CO2 concentration to no more than 450 ppmv. Detailed yet accessible, meticulously researched and reviewed, this work constitutes an indispensible textbook and reference for students and practitioners in sustainable energy and engineering. Online material includes: Excel-based computational exercises, teaching slides for each chapter, links to free software tools.

Enzymes produced by living cells are necessary ingredients for the chemical reactions that take place in the body. This textbook for advanced courses in enzyme chemistry and enzyme kinetics covers the field of steady-state enzyme kinetics from the basic principles inherent in the Henri equation to the expressions that describe the control of multi-enzyme pathways. Steady-state kinetic equations are derived with the use of the connection matrix method, and an algorithm is developed that can be implemented easily for computer-based derivation of the equations. Throughout the book emphasis is placed on a proper interpretation of the kinetic behavior of multi-reactant enzymic reactions and on the interpretation of control coefficients in terms of metabolic control. Problems are included at the end of each chapter and their solutions are found at the end of the book. This book will be particularly useful as a graduate text in biochemistry and chemistry courses.

This book differs from other organic chemistry textbooks in that it is not focused purely on the needs of students studying premed, but rather for all students studying organic chemistry. It directs the reader to question present assumptions rather than to accept what is told, so the second chapter is largely devoted to spectroscopy (rather than finding it much later on as with most current organic chemistry textbooks). Additionally, after an introduction to spectroscopy, thermodynamics and kinetics, the presentation of structural information of compounds and organic families advances from hydrocarbons to alcohols to aldehydes and ketones and, finally, to carboxylic acids.

This textbook is specifically designed for upper-division undergraduate or graduate students in life science or pre-medical majors including dentistry or pharmacology, who are required to take a biochemistry or medical biochemistry course, but who are not necessarily biochemistry majors. The book adopts a unique approach to the topic compared with other biochemistry textbooks currently available, in that each biochemical subject is introduced by a human disease relating the biochemical principles to be developed in that chapter. The goal is to make biochemistry more meaningful to the student who is not normally shown the connection between biochemistry and medicine. * Includes an abundance of figures* Emphasizes human biochemistry* Introduces each chapter with a relevant disease or clinical relationship

This textbook consists of six chapters. The first chapter highlights the concept of liquid crystals, including chemical structure, phase classification, defect and texture, and continuum theory. It has been carefully written to meet the needs of readers who do not specialize in liquid crystals. The second chapter is related to the theoretical description of liquid crystalline polymers, networks, and gels, which deals with subjects such as the formation of liquid crystallinity in the polymer system, the phase transition and phase diagram, the molecular weight effect, chain conformation, physics properties and so on. In Chapter 3, the molecular engineering of liquid crystalline polymers is introduced. The molecular composition and the molecular weight play essential roles in the molecular design, which are reviewed in detail. In addition, some unusual liquid crystalline polymers are discussed. Chapter 4 is devoted to the phase identification of liquid crystalline polymers. The techniques involved cover polarizing microscopy, thermal analysis, X-ray diffraction, and other areas. Chapters 5 and 6 summarize the properties and applications of liquid crystalline polymers: Chapter 5 deals mainly with mechanical performance in fiber and composites; Chapter 6 presents the elasticity, viscosity and rheology of liquid crystalline polymers, as well as other important properties.

The third edition of this textbook on the processing and formulation of oils in the food industry has been expanded to include the health implications of essential fatty acids, new concerns about trans fats and additional research on the use of sterols, stanols and other additives. O'Brien, noted food engineering expert, has used over 45 years' worth of materials from trade journals, patents and personal experience to assist food scientists in developing techniques that are both cost- effective and healthy. The author also provides a new chapter on quality management during such processes as bleaching, hydrogenation, blending, deodorization and packaging. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)

Drawing from the various disciplines of food science, this textbook covers most major milk products, including butter, yogurt, cheese, concentrated and dried milk, desserts, and ice cream. It discusses the processing technology involved in producing each, and product-related issues like criteria for acceptability. Varnam is a consultant microbiologist. Sutherland studies food and beverage microbiology at the AFRC Institute of Food Research. Originally published by Chapman and Hall, 1994. Annotation c. Book News, Inc., Portland, OR (booknews.com)

The textbook that has defined the field of immunology since 1984 is now in its thoroughly revised and updated Sixth Edition. This comprehensive, up-to-date text will be of interest to graduate students, post-doctoral fellows, basic and clinical immunologists, microbiologists and infectious disease physicians, and any physician treating diseases in which immunologic mechanisms play a role. This edition features expanded coverage of regulatory T cells, innate immunity, and dendritic cells. Additional chapters on cytokines are also included. A companion Website offers the fully searchable text, plus all illustrations in full color and comprehensive lists of references.

This is an introductory textbook on molecular biopharmaceutics. "Molecular Biopharmaceutics" involves the study of drug absorption, transport and delivery at the molecular level. In particular, increasing knowledge of the molecular structure and function of membrane transporter proteins and the understanding that they play a significant role in drug transport across biological membranes has lead to growing interest in this area from the pharmaceutical industry. This emerging knowledge of membrane transporter proteins has implications for understanding drug disposition and in turn for the development of more effective drug delivery strategies. The text provides an overview of the field of molecular biopharmaceutics, and explains its importance in drug development. It focuses on describing the interplay between the chemistry of drug molecules and membrane transporters, and will guide researchers in setting up experiments that may help in understanding the mechanisms and kinetics involved in drug absorption, transport and delivery.

Transforming our energy supplies to be more sustainable is seen by many to be the biggest challenge of our times. In this comprehensive textbook, L.D. Danny Harvey sets out in unprecedented detail the path we must take to minimize the effects that the way we harness energy will have on future climate change. The book opens by highlighting the importance of moving to low carbon technologies for generation, then moves on to explain the functioning, potential and social/environmental issues around: solar energy  wind energy biomass energy geothermal energy hydroelectric power ocean energy  nuclear energy. It also covers the options for carbon capture and storage and the contexts in which low carbon energy can best be utilized (potential for community integrated systems, and the hydrogen economy). The book closes with scenarios that combine the findings from its companion volume (concerning the potential for limiting future energy demand) with the findings from this volume (concerning the cost and potential of C-free energy systems) to generate scenarios that succeed in limiting future atmospheric CO2 concentration to no more than 450 ppmv. Detailed yet accessible, meticulously researched and reviewed, this work constitutes an indispensible textbook and reference for students and practitioners in sustainable energy and engineering. Online material includes: Excel-based computational exercises, teaching slides for each chapter, links to free software tools.

Transforming our energy supplies to be more sustainable is seen by many to be the biggest challenge of our times. In this comprehensive textbook, L.D. Danny Harvey sets out in unprecedented detail the path we must take to minimize the effects that the way we harness energy will have on future climate change. The book opens by highlighting the importance of moving to low carbon technologies for generation, then moves on to explain the functioning, potential and social/environmental issues around: solar energy  wind energy biomass energy geothermal energy hydroelectric power ocean energy  nuclear energy. It also covers the options for carbon capture and storage and the contexts in which low carbon energy can best be utilized (potential for community integrated systems, and the hydrogen economy). The book closes with scenarios that combine the findings from its companion volume (concerning the potential for limiting future energy demand) with the findings from this volume (concerning the cost and potential of C-free energy systems) to generate scenarios that succeed in limiting future atmospheric CO2 concentration to no more than 450 ppmv. Detailed yet accessible, meticulously researched and reviewed, this work constitutes an indispensible textbook and reference for students and practitioners in sustainable energy and engineering. Online material includes: Excel-based computational exercises, teaching slides for each chapter, links to free software tools.

First published in 1989, Physiology of Crop Yield was the first student textbook to digest and assimilate the many advances in crop physiology, within a framework of resource capture and use. Retaining the central core of the first edition, this long-awaited second edition draws on recent developments in areas such as phenology, canopy dynamics and crop modelling, and the concepts of sustainable crop production. A broad perspective is developed, from the gene through the plant and crop to the ecosystem, covering:Advances in molecular biology relating to crop science Limitation of crop yield by the supply of water or nitrogen Global climate change and its impact on crop modelling Physiological aspects of crop quality A wider range of species, with emphasis on wheat, maize and soybeanThis book will be a valuable tool for advanced undergraduate and postgraduate students of agricultural science, plant science, applied ecology and environmental science. It will be an essential addition to all libraries in universities and relevant research establishments.

Exercise Endocrinology is the only comprehensive textbook dealing with the endocrine physiology of exercise. The book serves both as a valuable introduction to endocrinology and as an integrative overview of exercise endocrinology. The text will help you understand the basics of endocrinology while giving you the most current information on endocrine physiology research.What makes Exercise Endocrinology unique is its organization by functional responses of hormones rather than by their organs and tissue origins. In addition, the book integrates autonomic physiology with endocrinology to present the most thorough review available of the autonomic nervous system's involvement in exercise. Written by a highly acclaimed exercise scientist and endocrinology researcher, Exercise Endocrinology is well organized and includes references, illustrations, and tables that will help you do the following:-Compare hormone sources and effects-Categorize hormones, receptors, organ sources, and actions-Understand hormone functions (with specific consideration for fluid regulation, immunology, fuel use, stress responses, biological rhythms, and physical performance)-Recognize hormone agonists and antagonists-Be aware of the influence of exercise and hormones on human healthThe text devotes substantial attention to the chemical mediation of hypertension, diabetes, hyperlipidemia, and obesity. It also combines the study of growth and energy regulation to clarify how chemical mediators cause partitioning of energy down these separate pathways. The practical value of Exercise Endocrinology will appeal to students and exercise scientists, and the book will also be a valuable reference for health professionals who use exercise in disease prevention and rehabilitation.

Transforming our energy supplies to be more sustainable is seen by many to be the biggest challenge of our times. In this comprehensive textbook, L.D. Danny Harvey sets out in unprecedented detail the path we must take to minimize the effects that the way we harness energy will have on future climate change. The book opens by highlighting the importance of moving to low carbon technologies for generation, then moves on to explain the functioning, potential and social/environmental issues around: solar energy  wind energy biomass energy geothermal energy hydroelectric power ocean energy  nuclear energy. It also covers the options for carbon capture and storage and the contexts in which low carbon energy can best be utilized (potential for community integrated systems, and the hydrogen economy). The book closes with scenarios that combine the findings from its companion volume (concerning the potential for limiting future energy demand) with the findings from this volume (concerning the cost and potential of C-free energy systems) to generate scenarios that succeed in limiting future atmospheric CO2 concentration to no more than 450 ppmv. Detailed yet accessible, meticulously researched and reviewed, this work constitutes an indispensible textbook and reference for students and practitioners in sustainable energy and engineering. Online material includes: Excel-based computational exercises, teaching slides for each chapter, links to free software tools.

First published in 1989, Physiology of Crop Yield was the first student textbook to digest and assimilate the many advances in crop physiology, within a framework of resource capture and use. Retaining the central core of the first edition, this long-awaited second edition draws on recent developments in areas such as phenology, canopy dynamics and crop modelling, and the concepts of sustainable crop production. A broad perspective is developed, from the gene through the plant and crop to the ecosystem, covering:Advances in molecular biology relating to crop science Limitation of crop yield by the supply of water or nitrogen Global climate change and its impact on crop modelling Physiological aspects of crop quality A wider range of species, with emphasis on wheat, maize and soybeanThis book will be a valuable tool for advanced undergraduate and postgraduate students of agricultural science, plant science, applied ecology and environmental science. It will be an essential addition to all libraries in universities and relevant research establishments.

The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology.This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.

Most "pathology" textbooks cover diseases and disease processes from the perspective of description (what does it look like and what are its characteristics), risk factors, disease-causing agents, and to some extent, cellular mechanisms. However, these books typically contain very sparse coverage (if any at all) of molecular mechanisms of disease. The reason for this is partially historical - most major forms of disease have been known for a long time, but the molecular basis of these diseases are not always known or have been elucidated only recently. Nevertheless, our overall understanding of the molecular and genetic mechanisms of the pathogenesis of most major human diseases has been advancing at a significant pace over the last two decades. As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, there is a need for a new textbook where molecular mechanisms represent the focus. Molecular Pathology focuses on the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine.Molecular Pathology is appropriate as a classroom teaching tool for medical students, biomedical graduate students, and some allied health students. In addition, it should be used as a reference book for practicing basic scientists and physician scientists that perform disease-related research. Further, this textbook will be valuable for pathology residents and other postdoctoral fellows who need to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. * Exam Master® web site will host "Self-assessment" questions that students can use to study for the molecular section of the board exam* Companion Web Site - would host a complete set of PowerPoint slides: to include images from the book and additional images for teaching; course materials; lecture materials* Teaches from the perspective of "integrative systems biology, ” which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease* Outlines the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology* Explains the practice of "molecular medicine” and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine

The "ULLA" series is a new and innovative series of introductory textbooks for postgraduate students in the pharmaceutical sciences. This new series is produced by the ULLA Consortium (European University Consortium for Advanced Pharmaceutical Education and Research). The Consortium is a European academic collaboration in research and teaching of the pharmaceutical sciences that is constantly growing and expanding. Before a drug substance can be tested in man, a set of toxicology studies must be carried out in animals and in vitro to ensure, as far as possible, safety for the test subjects. Toxicity studies involve assessment of acute, repeated dose and chronic toxicities, evaluation of potential effects on vital organs, reproductive and developmental toxicity studies, and carcinogenicity studies. This book covers a limited number of areas of drug toxicity which address the major issues including registration requirements of new drugs and pharmacovigilance. It also provides an overview of the methodology and requirements of pre-clinical safety assessment of new medicines. Mechanisms by which drugs cause toxic effects in living organisms, and problems in the toxicity of specific agents are covered, as are regulatory issues, pharmacovigilence, and clinical toxicology. There is no other textbook at this level dedicated to pharmaceutical toxicology, and this new title in the "ULLA" series fills a definite gap in the market.

The long-awaited third edition of this popular textbook, which has been unavailable for several years, is completely revised and updated. It retains the successful format of previous editions, dealing with the nature, actions and roles of hormones among vertebrate animals. Special emphasis is placed on the evolution and origins of hormones and their receptors; the role of hormones in the physiological coordination of vertebrates; and each endocrine process in the context of the organism's physiology, ecology, and evolution. Comparative Vertebrate Endocrinology discusses the intimate physiology of the endocrine system and the pivotal role of hormones in coordinating basic body processes such as nutrition, reproduction, calcium metabolism, and osmoregulation, as well as their contributions to animal coloration, molting, and development. The species included range from lower chordates to mammals, including marsupials.

This introductory textbook examines the issues of human reproduction common to a variety of advanced school and beginning university courses. It covers in detail the physiology of the human reproductive system, the production of gametes, fertilisation, pregnancy, birth, lactation and contraception. Sensitive issues such as infertility, abortion and embryo research are discussed with careful consideration of the moral and ethical issues involved.

Most textbooks on neurodegenerative disorders have used a classification scheme based upon either clinical syndromes or anatomical distribution of the pathology.  In contrast, this book looks to the future and uses a classification based upon molecular mechanisms, rather than clinical or anatomical boundaries.  Major advances in molecular genetics and the application of biochemical and immunocytochemical techniques to neurodegenerative disorders have generated this new approach. Throughout most of the current volume, diseases are clustered according to the proteins that accumulate within cells (e.g. tau, α-synuclein and TDP-43) and in the extracellular compartments (e.g. β-amyloid and prion proteins) or according to a shared pathogenetic mechanism, such as trinucleotide repeats, that are a feature of specific genetic disorders. Chapters throughout the book conform to a standard lay-out for ease of access by the reader and are written by a panel of International ExpertsSince the first edition of this book, major advances have been made in the discovery of common molecular mechanisms between many neurodegenerative diseases most notably in the frontotemporal lobar degenerations (FTLD) and motor neuron disease or amyotrophic lateral sclerosis.This book will be essential reading for clinicians, neuropathologists and basic neuroscientists who require the firm up-to-date knowledge of mechanisms, diagnostic pathology and genetics of Neurodegenerative diseases that is required for progress in therapy and management.

Ceramic materials that are specially developed for use as medical and dental implants are termed bioceramics. They include alumina and zirconia, bioactive glasses, glass-ceramics, coatings and composites, hydroxyapatite and resorbable calcium phosphates, and radiotherapy glasses. This is a textbook in the field which is growing rapidly in clinical applications including orthopaedics, otolaryngology, maxillo-facial and plastic surgery, oral surgery, periodontology, and tumour therapy. Fourteen chapters describe the processing, compositions, properties, surface chemistry, tissue response and clinical applications. There are also chapters on characterization and quality assurance testing, and the procedures that must be followed to satisfy regulatory requirements. A forecast of future needs of the field and appendices that summarize the relevant standards and test methods complete this book. The purpose of the book is to summarize and synthesize the very large and disparate body of literature in the field. Thus, it is easy to use as a textbook for an undergraduate or first year graduate course, industrial short course, or reference source.

Thoroughly updated, incorporating around 25 % new material, Sewald/Jakubke remains the only modern and scientifically up-to-date advanced textbook on peptide biochemistry, distilling the knowledge of hundreds of publications into a highly readable synopsis of this diverse field. The authors explain the broad fundamentals of peptide synthesis and structure, systematically addressing important families of biologically active peptides, and adopting an interdisciplinary approach that covers application areas in biotechnology, pharmaceutical science, and biomedicine. One major focus is on such "hot" research topics as pseudopeptides, peptidomimetics, and combinatorial synthesis.This new edition also features study questions for each learning unit, for easier self-study and classroom teaching.